Table 1.

Markers of inflammation during two 4-day sojourns in NX and HH

	M0	M1	E1	M2	M3	M4	M5
High-sensitivity C-reactive protein, mg·dL−1
NX	0.10 [0.05–0.20]	0.10 [0.05–0.20]	0.10 [0.05–0.10]	0.05 [0.05–0.10]	0.05 [0.05–0.10]	0.05 [0.05–0.10]	0.05 [0.05–0.20]
Values < detection threshold*	5/11	5/11	5/11	6/11	8/11	7/11	7/11
HH	0.10 [0.05–0.20]	0.10 [0.05–0.20]	0.10 [0.05–0.20]	0.10 [0.06–0.20]	0.10 [0.05–0.20]	0.10 [0.05–0.20]	0.10 [0.05–0.20]
Values < detection threshold*	4/12	3/11	4/12	3/12	4/12	4/12	3/11
Interleukin-6, pg·mL−1
NX	1.60 [0.75–2.6]	1.80 [0.75–4.60]	1.50 [0.75–1.70]	0.75 [0.75–1.70]	0.75 [0.75–0.75]	0.75 [0.75–0.75]	0.75 [0.75–0.75]
Values < detection threshold*	5/11	5/11	5/11	8/11	11/11	11/11	9/11
HH	0.75 [0.75–1.78]	0.75 [0.75–1.90]	1.23 [0.75–2.00]	0.75 [0.75–1.70]	0.75 [0.75–1.73]	0.75 [0.75–1.39]	0.75 [0.75–1.80]
Values < detection threshold*	7/12	6/11	6/12	8/12	8/12	9/12	7/11

Values are medians [25–75% interquartile ranges]. *Values below detection threshold were estimated as half that threshold (i.e., 0.05 mg·dL⁻¹ for high-sensitivity C-reactive protein and 0.75 pg·mL⁻¹ for interleukin-6). The number of values below the detection threshold is provided for each time point. NX, normoxia; HH, hypobaric hypoxia; M0, morning presojourn; M1–M5, first to fifth morning of the sojourns, respectively; E1, first evening of the sojourns.