Table 1.

Preexercise values compared between the amiloride and placebo trials

	n	Placebo	Amiloride	Mean Diff	95% CI	Cohen’s d	P
Maximal voluntary contraction, kg	10	40.5 ± 3.6	46.5 ± 20.2	6.0 ± 17.3	−4.7/16.7	−0.347	0.15
Assigned contraction intensity, kg	10	15.7 ± 4.5	16.8 ± 7.2	1.0 ± 5.8	−2.5/4.6	0.187	0.28
Mean arterial pressure, mmHg	10	83 ± 7	83 ± 7	0 ± 7	−5/4	0.039	0.45
Systolic blood pressure, mmHg	10	112 ± 9	114 ± 10	1 ± 6	−5/2	0.251	0.22
Diastolic blood pressure, mmHg	10	71 ± 7	71 ± 8	0 ± 8	−5/5	−0.028	0.46
Heart rate, beats/min	10	60 ± 6	62 ± 5	2 ± 4	−5/0	0.475	0.16
MSNA burst rate, bursts/min	7	22.5 ± 10.0	17.8 ± 10.0	−4.7 ± 7.4	−10.2/0.8	0.632	0.07
MSNA burst incidence, burst/100 beats	7	35.3 ± 15.1	27.3 ± 15.0	−8.0 ± 10.6*	−15.9/−0.1	0.758	0.04
Total MSNA, a.u.	7	408.8 ± 175.3	372.5 ± 195.7	−36.2 ± 126.4	−129.9/57.3	0.287	0.23

Data are means ± SD for placebo, amiloride, and mean diff; n, number of participants. CI, confidence intervals; mean diff, mean difference; MSNA, muscle sympathetic nerve activity. *Significant difference between conditions.