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. 2022 Oct 12;323(6):R875–R888. doi: 10.1152/ajpregu.00190.2022

Table 2.

Markers of exercise tolerance compared between amiloride and placebo trials

n Placebo Amiloride Mean Diff 95% CI ηp2 P
Time to failure, s 10 570.1 ± 255.0 639.6 ± 264.1 69.4 ± 63.2* 30.3/108.6 0.573 <0.01
Time tension index, kg·s/1,000a 10 6.72 ± 4.31 8.16 ± 5.68 1.44 ± 0.63* −361.0/3244.2 0.496 0.02
Pain, cm 10 3.1 ± 2.5 3.5 ± 3.2 0.4 ± 1.7 −1.5/0.6 0.06 0.46
RPE 10 16 ± 2 16 ± 2 0 ± 0 0/0 0.18 0.19

Data are means ± SD for placebo, amiloride, and mean diff; n, number of participants.

aDifferences in assigned contraction intensity included as covariate. Mean diff, mean difference; ηp2, partial η squared; RPE, rating of perceived exertion. *Significant difference between conditions.