Table 2.
Cytokine | Time | Patinet 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 |
---|---|---|---|---|---|---|---|---|---|---|---|
IL-6 (pg/mL) | Before irAEs | 3.05 | 3.96 | 5.35 | 3.10 | 3.44 | 5.19 | 0.00 | 5.17 | 15.43 | 5.46 |
irAEs | 23.03 | 10.45 | 5.05 | 5.89 | 7.72 | 8.87 | 8.95 | 2.64 | 25.00 | 11.01 | |
IFN-γ (pg/mL) | Before irAEs | 7.51 | 0.00 | 13.41 | 8.51 | 2.76 | 3.83 | 6.70 | 0.00 | 21.58 | 0.00 |
irAEs | 5.82 | 2.52 | 6.82 | 2.59 | 4.45 | 9.54 | 4.25 | 2.81 | 17.45 | 5.87 |
The normal range of IL-6 is < 5.4 pg/mL, and the normal range of IFN-γ is < 23.01 pg/mL. IL-6 = interleukin-6, INF-γ = interferon-γ, irAEs = inhibitors-related adverse events.