Table 2. Methodological quality of studies included in the final analysis based on the Newcastle-Ottawa Scale^a for assessing the quality of cohort studies (n = 12).

Cohort studies (N = 12)	Selection				Comparability	Outcome			Total
	Representativeness of the exposed cohort	Selection of the non-exposed cohort	Ascertainment of exposure	Outcome of interest was not present at start of study	Control for important factor or additional factor	Assessment of outcome	Follow-up long enough for outcomes to occur	Adequacy of follow-up of cohorts
Klag et al., 200215	0	1	0	1	2	0	1	1	6
Winkelmayer et al., 2005 (NHS1)16	0	1	0	1	2	0	1	1	6
Winkelmayer et al., 2005 (NHS1)16	0	1	0	1	2	0	1	1	6
Hu et al., 200717	1	1	0	1	2	1	1	1	8
Palatini et al., 200718	1	1	0	1	2	1	0	1	7
Uiterwaal et al., 200719	1	1	0	1	2	1	1	0	7
Grosso et al., 201620	1	1	0	1	2	1	0	1	7
Palatini et al., 201621	1	1	0	1	2	1	1	1	8
Rhee et al., 201622	0	1	0	1	2	1	0	1	7
Chei et al., 201823	1	1	0	1	2	0	1	0	6
Navarro et al., 201924	1	1	0	1	2	0	1	1	7
Miranda et al., 202125	1	1	1	1	2	1	0	1	8
Tan et al., 202126	1	1	0	1	2	1	1	0	7

^aEach study can be awarded a maximum of one star for each numbered item within the selection and exposure categories, while a maximum of two stars can be given for the comparability category.