. 1999 Sep;67(9):4628–4636. doi: 10.1128/iai.67.9.4628-4636.1999

TABLE 2.

Prechallenge safety—clinical signs following vaccination with NOBL SC-54 or various vaccine candidate strains

Strain or group	Time^a	Mortality (%)^b	Morbidity score (%)^b	Diarrhea score (%)^b	% of pigs culture positive (vaccine strains)	ADG (kg)	Mean temp (°C)^c
Nonvaccinated, challenged	Pre	0	0	1.0			39.4
	Post	0	0	1.2	0	0.73	40.2^*
Nonvaccinated, nonchallenged	Pre	0	0	0			39.6
	Post	0	0	0	0	0.69	40.3^*
NOBL SC-54	Pre	0	0	0			39.8
	Post	0	0	4.2	0	0.64	40.4^*
χ3246	Pre	0	0	0			NT
	Post	20.0	23.3	46.2	80.0	−0.03	NT
χ3781	Pre	0	0	8.3			39.4
	Post	0	0	1.8	0	0.65	40.9^**
χ3923	Pre	0	0	3.1			39.7
	Post	0	0	1.2	0	0.65	40.6^*
χ4186	Pre	0	0	1.0			39.5
	Post	0	0	2.4	0	0.66	41.2^**
χ4497	Pre	0	0	1.0			39.4
	Post	0	0	0	0	0.70	40.0^*
χ4522	Pre	0	4.1	5.2			39.8
	Post	0	0	1.2	0	0.69	40.4^*
χ4814	Pre	0	0	4.2			39.7
	Post	0	0	3.0	0	0.70	40.2^*

Pre, mean for the 4 days prior to vaccination; post, mean for the 1-week period postvaccination except for temperatures.

Maximum possible severity is 100%.

“Pre” values are the mean temperatures for the 4 days before vaccination. “Post” values are the mean maximum temperatures for the post vaccination period. NT, not tested. * and **, values in the same column with different superscripts are significantly different (P < 0.05).