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. 2022 Nov 8;13:1038401. doi: 10.3389/fimmu.2022.1038401

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Copyright © 2022 Liu, Zhou, Yan, Cheng, Fan, Xu, Zheng, Bai, Li, Li and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subclustering of macrophages and DCs. (A) UMAP plot of liver macrophages and DCs showing a six-cluster distribution. (B) Feature plots of marker gene expression in six clusters. (C) Heatmap showing the marker genes of each cluster mentioned in (A). (D) Gene enrichment for classical cell type M1 and M2 in comparisons with the macrophage and DCs subsets in NAFL. (E) GO BP terms enriched in the indicated subset. The gene list is the marker genes of each cluster, colored by -log₁₀ (P value), scaled by row.