Figure 3.

Gene expression heterogeneity and gene expression upregulation by ApoA4 knockout in macrophages and DCs. (A) Fraction of each macrophage and DC subset in WT and KO mice. (B) Volcano plot showing DEGs in macrophages and DCs between WT and KO mice. Genes upregulated in WT are shown in blue. GO (C) and KEGG (D) analyses, respectively, with the gene set in (B), cut-off = 0.5. (E) GSEA plots of enriched pathways upregulated in KO macrophage and DC subsets. (F) Violin plots showing the expression of function-related genes in (C, D) across six groups.