Fig. 1.

An illustration of how the DIVIDE parameters reflect the underlying diffusion tensor distribution in eight different substrates that have the same mean diffusivity (MD = 1 µm²/ms). The first column shows an increase in the variance of isotropic diffusivities (MKI) and the third column shows an increase in orientation dispersion. The first row shows an increase in macroscopic anisotropy (MKA), which affect fractional anisotropy (FA) on the macroscopic and microscopic (µFA) levels. The bottom row shows an increase in microscopic anisotropy with total orientation dispersion, which will leave FA = 0.The figure was adapted and reproduced, with permission, from Szczepankiewicz [18].