Table 4.

Main advances in the study of glanders based on the scientific articles published by the UFRPE group

Year	Author	Title	Advances
2000	Mota et al. [4]	Glanders in equidae in the states of Pernambuco and Alagoas	First record of the re-emergence of Glanders in Brazil
2004	Mota et al.[8]	Influence of bacteria isolated from upper airway lesions on microbiological diagnosis of Glanders in equidae	Advancement and improvement in the microbiological diagnosis of Glanders
2004	Rabelo et al.[9]	Hematological and biochemical aspects in mules naturally infected by Burkholderia mallei	First hematological and biochemical study of mules naturally infected with Burkholderia mallei
2005	Mota et al. [10]	Biochemical characterization and in vitro antimicrobial sensitivity profile of Burkholderia mallei samples isolated from equidae from the northeastern region of Brazil	First antimicrobial sensitivity profile study of Burkholderia mallei field isolates
2006	Mota [2]	Etiological, epidemiological and clinical aspects of Glanders	Literature review as support for scientific dissemination of the Glanders
2006	Rabelo et al. [11]	Clinical indicators in mules naturally infected by Burkholderia mallei	First study on clinical indicators in mules naturally infected with Burkholderia mallei
2007	Mota et al. [12]	Serum Proteinogram in mules naturally infected by the Burkholderia mallei	First study on serum proteinogram in mules naturally infected with Burkholderia mallei
2008	Mota et al. [13]	Clinical alterations in guinea pigs (Cavia porcellus) experimentally inoculated with Burhkolderia mallei field isolates of Glanders equidae	Establishment of an experimental model of Burkholderia mallei infection in guinea pigs
2009	Schmoock et al. [14]	DNA microarray-based detection and identification of Burkholderia mallei, Burkholderia pseudomallei, and Burkholderia spp.	Development of a rapid molecular assay for differentiation of Burkholderia spp. species
2009	Silva et al. [15]	Phenotypic and molecular characterization of Burkholderia mallei samples isolated in northeastern Brazil	First biochemical and molecular identification of Burkholderia mallei isolates in Brazil
2010	Mota et al. [18]	Glanders in donkeys (Equus asinus) in the state of Pernambuco, Brazil: a case report	First record of clinical and histopathological findings of Glanders in donkeys in Brazil
2012	Teles et al. [23]	Development and evaluation of an indirect ELISA test for the serological diagnosis of Glanders in equidae	Standardization of an indirect ELISA as a Glanders diagnostic tool
2013	Silva et al. [24]	Assessment of the effectiveness of the PPD-mallein produced in Brazil for diagnosing Glanders in mules	Production and evaluation of a national malleina as an alternative for the diagnosis and control of Glanders in Brazil
2014	Silva et al. [26]	Production and partial purification of PPD-malein for diagnosis of Glanders in equidae	-Production and evaluation of national malein as an alternative for the diagnosis and control of Glanders in Brazil
2019	Falcão et al. [34]	First record of Burkholderia mallei Turkey 10 strain originating from glanderous horses from Brazil	First registration of Burkholderia mallei turkey 10 strain in horses with Glanders in Brazil
2019	Fonseca-Rodríguez et al. [37]	Spatiotemporal Analysis of Glanders in Brazil	Epidemiological analysis of the distribution of Glanders foci in Brazil
2021	Rocha et al. [40]	Monitoring the outbreak of equine Glanders in Alagoas, Brazil: clinical, immunological, molecular, and anatomopathological findings	Clinical, serological and molecular monitoring of horses in a disease focus
2022	Falcão et al. [42]	Molecular characterization of Burkholderia mallei strains isolated from Brazil (2014–2017)	Genetic characterization B. mallei isolates obtained from Glanders Equidae in the states of Pernambuco and Alagoas