L-theanine treatment increased HGF secretion by ADSCs. A Quantitative results of cytokine array for secreted HGF from ADSCs with and without L-theanine treatment. ***Compared to control, p < 0.001. B Immunohistochemical staining of HGF in the liver sections of experimental animals with DEN treatment for 2, 4, or 8 weeks (DEN), respectively (2wk, 4wk, 8wk). DEN + ADSC: liver sections of DEN treatment followed with 4 weeks of ADSC treatment. DEN + ADSC + T: DEN-injected liver tissue slices with ADSCs pretreated with L-theanine. Arrow points to the brown positive HGF signal stain. The scale bar represents 25 μm. C Quantification of immunohistochemical HGF staining. Compared to DEN, #: p < 0.05, ##: p < 0.01. Compared to DEN + ADSC, $: p < 0.05. $$: p < 0.01