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. 2022 Sep 8;19(6):1321–1336. doi: 10.1007/s13770-022-00471-3

Fig. 2.

Fig. 2

Fig. 2

PRP promotes osteogenic and angiogenic differentiation in vitro. The ALP-positive cells and calcium deposition was more prominent in OM + PRP group compared with OM group (40 ×). PRP significantly promoted the formation of capillary-like tubes in AM + PRP group. A ALP activity after 7 days of osteogenic induction. B Absorbance of alizarin red staining after 14 days of osteogenic induction. C, D The number and average diameters of formed tubes after 24 h of angiogenic induction. E Relative expression of COL1A1 and OCN mRNA after 14 days of osteogenic induction. F,G The protein expression of COL I and OCN after 14 days of osteogenic induction. (Data in mean ± SD, n = 5, *p < 0.5, **p < 0.01, ***p < 0.001, OM = osteogenic medium, AM = angiogenic medium)