. 2022 Aug 24;145(11):3803–3815. doi: 10.1093/brain/awac226

Table 1.

Participant details including clinical visual acuity measures, psychophysical thresholds and fMRI data measures regarding the correspondence and correlation between the cone- and rod-driven cortical maps

Age group	Genotype	Visual acuity BCVA^a (LogMAR)			Cone sensitivity (threshold)		fMRI				pRF size^d	Post-treatment test^e
Age group	Genotype	Left eye	Right eye	Both	Square	Ridge	Intercept	Slope	AIC_W^b	CC_FL^c	pRF size^d	Post-treatment test^e
Pre-treatment treated patients with ACHM
Tr1	Child	CNGA3	0.94^f	0.92	0.86	0.24	0.30	125.25	−0.14	0	−0.05	1.69	6
Tr2	Child	CNGA3	0.76	0.80^f	0.70	0.46	N/A	32.29	0.02	0	−0.03	1.91	8
Tr3	Child	CNGB3	0.80	0.84^f	0.84	0.34	0.34	49.36	0.11	0	−0.03	1.68	14
Tr4	Child	CNGA3	0.78^f	0.76	0.78	0.34	0.38	33.15	0.17	0	0.12	1.45	14
Post-treatment treated patients with ACHM
Tr1	Child	CNGA3	0.92^f	0.84	0.82	0.16	0.16	−16.74	0.97	1	0.32	1.4
Tr2	Child	CNGA3	0.76	0.86^f	0.72	0.16	0.16	−8.27	0.82	1	0.60	1.76
Tr3	Child	CNGB3	0.56	0.72^f	0.54	0.34	0.34	32.04	−0.12	0	−0.11	1.47
Tr4	Child	CNGA3	0.78^f	0.72	0.70	0.34	0.34	−2.00	−0.06	0	0.02	1.31
Untreated patients with ACHM
Utr1	Child	CNGB3	1.04	1.00	0.94	0.34	0.46	43.78	0.29	0	−0.31	2.27
Utr2	Child	CNGB3	0.96	0.94	0.82	N/A	N/A	129.82	−0.08	0	−0.75	1.79
Utr3	Child	CNGB3	0.84	0.94	0.82	0.42	0.38	−422.50	−17.36	0	−0.03	1.86
Utr4	Child	CNGB3	0.90	0.90	0.86	0.34	0.30	85.97	0.29	0	0.70	1.46
Utr5	Child	CNGB3	0.86	0.96	0.90	0.52	0.38	32.74	0.50	0	0.12	1.53
Utr6	Child	CNGA3	0.86	0.92	0.92	0.46	N/A	−35.42	−4.64	0	0.12	2.3
Utr7	Child	CNGA3	0.76	0.72	0.72	0.38	0.30	64.89	2.02	0	0.11	1.2
Utr8	Adult	CNGA3	0.70	0.70	0.70	0.52	0.34	−3 × 10⁶	−2 × 10⁴	0	0.41	1.66
Utr9	Adult	CNGA3	0.90	0.80	0.84	0.46	0.38	−97.29	0.50	0	−0.03	1.42
Normal-sighted controls
C1	Child	Normal^g	N/A	N/A	0.02	0.16	0.16	2.20	1	1	0.86	1.92
C2	Child	Normal^g	N/A	N/A	−0.04	0.16	0.16	−4.97	1	1	0.74	1.56

N/A indicates missing data. Measures from Patients Tr1 and Tr2 are presented using bold text. AIC_W = Akaike iInformation Criterion Weight; CC_FL = Fisher–Lee correlation coefficient.

^{^a}

Best corrected visual acuity.

^{^b}

Akaike weight.

^{^c}

Fisher–Lee correlation coefficient.

^{^d}

Rod mean pRF size.

^{^e}

Duration between the pre- and post-treatment behavioural and fMRI measures (in months).

^{^f}

Treated eye.

^{^g}

Normal-sighted control with no ACHM.