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Gene-hydrogel microenvironments for regeneration in IVDD. (A) The construction of the gene-hydrogel microenvironment. (B) The Agomir@PEG was injected into the intervertebral space to construct the gene-hydrogel microenvironment. (C–E) The multi-functions provided by the gene-hydrogel microenvironment match the regeneration of IVDD. Reproduced with permission [153]. Copyright 2019, The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
