TABLE 2.

Association between peak BE12h > 6h and ICU mortality.

Parameters	Unadjusted OR	Adjusted OR	(95% CI)	p
Group without bicarbonate sodium used
Age	1.012	0.994	(0.980, 1.008)	0.387
Gender	0.802	0.821	(0.506, 1.333)	0.426
Apache II	1.164	1.168	(1.130, 1.208)	< 0.005
Peak BE12h > 6 h	2.102	2.359	(1.306, 4.260)	< 0.005
Lactate at admission	0.968	0.838	(0.618, 1.135)	0.253
BE at admission	1.044	0.911	(0.791, 1.051)	0.201
Peak lactate in first 6 h	0.996	1.140	(0.845, 1.538)	0.391
Peak BE in first 6 h	1.042	1.118	(0.964, 1.295)	0.140
Group with bicarbonate sodium used
Age	1.018	1.010	(0.993, 1.027)	0.247
Gender	1.147	1.561	(0.880, 2.768)	0.561
Apache II	1.146	1.136	(1.099, 1.174)	< 0.005
Peak BE12h > 6h	1.957	2.231	(1.054, 4.725)	0.036
Lactate at admission	1.059	0.975	(0.874, 1.088)	0.653
BE at admission	0.939	0.976	(0.894, 1.064)	0.576
Peak lactate in first 6 h	1.096	1.051	(0.950, 1.162)	0.335
Peak BE in first 6 h	0.878	0.968	(0.868, 1.079)	0.555

OR, odds ratio; CI, confidence interval; ICU, intensive care unit; APACHE II, Acute Physiology and Chronic Health Evaluation II; Peak BE12h > 6h, the peak value (minimal) BE value during the first 12 h after admission occurred after the first 6 h; BE, base excess.