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. 2022 Nov 8;13:1039329. doi: 10.3389/fpls.2022.1039329

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Copyright © 2022 Khoso, Hussain, Ritonga, Ali, Channa, Alshegaihi, Meng, Ali, Zaman, Brohi, Liu and Manghwar

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of drought stress and the role of WRKY TFs in mitigating drought stress. Drought stress causes ROS production, oxidative damage, ion toxicity, and nutrient imbalance impairing plant growth and development. WRKY TFs regulate the expression of stress response genes and ROS scavenging enzymes. Overexpression of various WRKY TFs reduces ion loss and ROS accumulation, induces leaf stomatal mobility, decreases water loss rate thereby promote water retention, which overall improves phenotypic morphology and plant survival.