TABLE 6.

Pathological features of the reported cases of inflammatory myofibroblastic tumor of the colon.

References #	Pathological features	Immunohistochemistry
(49)	Gross appearance: the cut surface of the tumor is tan, firm, trabeculated, and knobby. No necrosis, hemorrhage, or cyst. Microscopy features: the tissues have interlacing fascicles of elongated spindle cells and fusiform or stellate myxoid cells mixed with plasma cells, histiocytes, lymphocytes, and eosinophils. There is scarce mitosis.	+Ve: CD20, CD30, CD68, V-III, vimentin, SMA, and desmin. –Ve: cytokeratin and S-100.
(50)	Gross appearance: polypoid shape, ulcerated mucosa of the tumor. It has a yellow-gray color and rubbery feeling. Microscopy features: the lesion composed of spindle cells mixed with thick blood vessels, plasma cells and lymphocytes.	+Ve: CD34, SMA, CD68
(51)	Gross appearance: ND. Microscopy features: spindle cells mixed with inflammatory cells.	+Ve: SMA, desmin, cytokeratin, ALK, and S-100. –Ve: CD117.
(52)	Gross appearance: polypoid formation of 6 cm of diameter on a pedicle and ulcerated that occupied 85% of the lumen, with smooth and whitish external surface. Microscopy features: proliferation of spindle cells and abundant inflammatory infiltrate.	ND.
(53)	Gross appearance: ND. Microscopy features: extensive surface ulceration and was characterized by a proliferation of plump polygonal or more spindle-shaped cells with amphophilic cytoplasm and vesicular nuclei with prominent nucleoli. The lesion cells were distributed in a patternless fashion within a loose myxoid matrix, which contained numerous thin- walled blood vessels and prominent mixed inflammatory cells, including numerous plasma cells and lymphocytes.	+Ve: S100, keratin AE1/AE3 and desmin. –Ve: smooth muscle actin and anaplastic lymphoma kinase 1.
(54)	Gross appearance: 3.9 × 3.8 cm sized mass with fungating surface white to yellow color and invaded muscularis propria. Microscopy features: composed of a proliferation of spindle-shaped cells arranged in hyaline material with chronic inflammatory cells, composed mainly of plasma cells and lymphocytes, not neutrophils.	+Ve: smooth muscle actin and vimentin. –Ve: desmin, CD117 (c-kit), anaplastic lymphoma kinase (ALK)-1.
(55)	Gross appearance: oval shaped 12 cm diameter tumor with a firm tumor capsule and hemorrhagic with a cystic aspect. Microscopy features: dense areas with lymphocytes, plasma cells and history testing embedded in a loose spindle cell-like matrix of fibroblasts, myoblasts and histiocytes. Pseudotumor.	ND.
(56)	Gross appearance: polypoid mass (5.0 × 2.9 × 2.4 cm) Microscopy features: fibrosis in the central portion of the mass and marked infiltration of inflammatory cells, predominantly eosinophils in the periphery.	ND.
(57)	Gross appearance: 20 × 20 × 10 mm sized protruded tumor covered by intact mucosa with a central depressed area. Microscopy features: elongated cells with fascicular arrangement admixed with inflammatory cells, predominantly lymphocytes and few plasma cells.	+ Ve: desmin, SMA, perinuclear positivity for ALK, CD34, CD68 and CD117. –Ve: AE1/AE3, S100, B cell lymphoma 2, D99, CD56 chromogranin or synaptophysin and KIT.