Subject | Drug Discovery |
Specific subject area | Mitochondrial respiratory system |
Type of data | Figure |
How the data were acquired | Culture treatment assays using E. multilocularis protoscoleces were performed under aerobic and anaerobic conditions. The protoscoleces were treated with drug candidates in culture medium, then stained with trypan blue between day 0 and day 7, and subsequently counted by microscopy. |
Data format | Raw Analyzed |
Description of data collection | E. multilocularis protoscoleces were treated with three anti-echinococcal drug candidates (atovaquone, mefloquine, and 3-bromopyruvic acid) at a final concentration of 50 μM in each culture medium. Viability of protoscoleces was determined by microscopic analysis of more than 120 protoscoleces per well to exclude the contribution of trypan blue. |
Data source location | Institution: Hokkaido Institute of Public Health City: Sapporo Country: Japan Latitude and longitude (and GPS coordinates) for collected samples/data: 43°04′58.804′'N; 141°19′59.769′'E |
Data accessibility | https://data.mendeley.com/datasets/8gx4p2x5vw/1 |
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