Table 1.
Overview of participants and analysed lesions.
| MS | CIS | Cluster headache | Migraine | SLE | NMOSD | Diabetes mellitus | Ageing healthy controls | Total | |
|---|---|---|---|---|---|---|---|---|---|
| Number of patients (female) | 166 (110) | 88 (59) | 3 (1) | 21 (18) | 19 (16) | 30 (26) | 18 (10) | 217 (140) | 562 (380) |
| Mean age [SD] | 37.3 [7.4] | 32.6 [7.7] | 49.3 [12.6] | 40.8 [8.7] | 32.5 [9.5] | 46.5 [11.8] | 68.3 [14.0] | 64.1 [18.1] | 48.4 [17.8] |
| Symptom duration, mean (range) | 6.5 (0–30.5) | 0.3 (0–2.5) | – | – | – | 2.9 (0–9.6) | – | – | – |
| White matter lesions analysed | |||||||||
| No. of patients with ⩾1 WML, (%) | 164 (98.8) | 84 (95.4) | 2 (66.7) | 21 (100.0) | 15 (78.9) | 18 (60.0) | 18 (100) | 163 (75.1) | 485 (86.3) |
| No. of lesions | 3065 | 922 | 19 | 266 | 77 | 171 | 355 | 1142 | 6017 |
| Median no. per patient (range) | 17 (0–61) | 7 (0–54) | 9.5 (4–15) | 10 (1–38) | 4 (0–12) | 1 (0–38) | 17.5 (1–66) | 3 (0–30) | 7 (0–66) |
| Paramagnetic rim lesions | |||||||||
| No. of patients with ⩾1 PRL, (%) | 38 (22.9) | 23 (26.1) | 0 | 0 | 0 | 0 | 1 (5.6) | 0 | 62 (11.3) |
| No. of lesions (%) | 72 (2.3) | 57 (6.2) | 0 | 0 | 0 | 0 | 1 (0.3) | 0 | 130 (2.2) |
| Median no. per patient (range) | 0 (0–6) | 0 (0–8) | 0 | 0 | 0 | 0 | 0 (0–1) | 0 | 0 (0–8) |
MS: multiple sclerosis; CIS: clinically isolated syndrome; NMOSD: neuromyelitis optica disorder; SD: standard deviation; SLE: systematic lupus erythematosus; WML: white matter lesion; PRL: paramagnetic rim lesions.