Figure 2: Specific Subjective Response Item Models.

Note: All parameters are standardized estimates; Treatment is coded as 1=Naltrexone, 0=Placebo. At the between-person level, naltrexone treatment was directly associated with feeling less impaired, and there were significant indirect effects of naltrexone medication on all subjective response items, such that naltrexone was associated with blunted subjective response through lighter drinking. At the within-person level, taking 2 (vs. 1) pills was associated with feeling more buzzed, and there were significant indirect effects of medication dosage on all subjective response items through drinking, such that taking 1 (vs. 0) pills was associated with weaker subjective response through lighter drinking, and taking 2 (vs. 1) pills was associated with stronger subjective response through heavier drinking. ** P < .01, * P < .05, † P < .10