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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Alcohol Clin Exp Res. 2022 Feb 17;46(3):477–491. doi: 10.1111/acer.14780

Figure 3. Intense Subjective Response Model.

Figure 3.

Note: All parameters are standardized estimates; Treatment is coded as 1=Naltrexone, 0=Placebo. At the between-person level, naltrexone treatment was directly associated with feeling less intense subjective response, and there were significant indirect effects of naltrexone medication on intense subjective response, such that naltrexone was associated with blunted intense subjective response through lighter drinking. At the within-person level, there were significant indirect effects of medication dosage on intense subjective response through drinking, such that taking 1 (vs. 0) pills was associated with weaker intense subjective response through lighter drinking and taking 2 (vs. 1) pills was associated with stronger intense subjective response through heavier drinking. ** P < .01, * P < .05, † P < .10