TABLE 2.
Summary of cloned H. pylori antigen families
| Family | No. of clones | Urease AB hybridization oligonucleotide A and B | Protein molecular mass (kDa) | Protein N-terminal sequence | Protein identity (from database) |
|---|---|---|---|---|---|
| A | 5 | Yes | ∼62 | MKKISRKEYV | Urease B subunita |
| ∼33 | MKLTPKELDKLMLHRAGE | Urease A subunita | |||
| B | 14 | No | ∼19 | MLNQVLLKLGMSVKAAMV | Lpp20a |
| ∼17 | Not determined | Mature Lpp20 | |||
| C | 10 | No | ∼13 | MISKEEVLEYIGSLS | L7/L12b, ribosomal protein |
| E | 1 | No | ∼36 | Not determined | Unknown |
| F | 1 | No | ∼55 | AKEIKFVDAARNLFF | HspBa |
| G | 2 | No | ∼50 | MFGFKQLQLQFSQK | Unknown |
| H | 1 | No | ∼29 | Not determined | Unknown |
a
N-terminal sequences were compared with those in the Swiss-Prot/GenPeptide database.
b
Data from DNA sequence analysis.