Table 1. Trends in Hysterectomy-Corrected Cervical Cancer Incidence Rates (2001-2019): NPCR and SEER Database.
| Cases from 2001-2019, No. (%) | Yeara | Rateb | APC (95% CI), % | P value | ||
|---|---|---|---|---|---|---|
| Year 1c | Year 2d | |||||
| Overall | 227 062 (100) | 2001-2019 | 12.39 | 9.80 | −1.2 (−1.6 to −0.9) | <.001 |
| Age group, y | ||||||
| <24 | 2266 (1.0) | 2001-2012 | 0.29 | 0.24 | −3.1 (−4.8 to −1.4) | .002 |
| 2012-2019 | 0.24 | 0.08 | −12.4 (−16.6 to −8.0) | <.001 | ||
| 25-29 | 10 001 (4.4) | 2001-2004 | 6.80 | 5.45 | −7.4 (−14.9 to 0.9) | .07 |
| 2004-2016 | 5.45 | 5.36 | −0.7 (−1.9 to 0.5) | .24 | ||
| 2016-2019 | 5.36 | 4.01 | −7.5 (−15.8 to 1.7) | .10 | ||
| 30-34 | 20 679 (9.1) | 2001-2012 | 12.77 | 10.14 | −2.3 (−2.8 to −1.7) | <.001 |
| 2012-2019 | 10.14 | 11.60 | 2.5 (1.4 to 3.6) | <.001 | ||
| 35-39 | 26 630 (11.7) | 2001-2019 | 15.69 | 14.38 | −0.3 (−0.8 to 0.1) | .09 |
| 40-44 | 29 961 (13.2) | 2001-2019 | 19.70 | 16.81 | −0.3 (−0.8 to 0.1) | .13 |
| 45-49 | 28 088 (12.4) | 2001-2019 | 20.18 | 18.54 | −0.5 (−0.9 to 0) | .04 |
| 50-54 | 24 877 (11.0) | 2001-2005 | 21.68 | 17.40 | −4.7 (−8.4 to −0.8) | .02 |
| 2005-2019 | 17.40 | 17.48 | −0.4 (−1.0 to 0.2) | .19 | ||
| 55-59 | 22 434 (9.9) | 2001-2005 | 24.16 | 18.47 | −6.2 (−10.3 to −1.8) | .009 |
| 2005-2019 | 18.47 | 18.12 | −0.8 (−1.4 to −0.2) | .01 | ||
| 60-64 | 18 366 (8.1) | 2001-2019 | 25.51 | 19.23 | −2.1 (−2.7 to −1.4) | <.001 |
| 65-69 | 14 566 (6.4) | 2001-2019 | 31.05 | 17.39 | −3.2 (−3.8 to −2.5) | <.001 |
| 70-74 | 10 640 (4.7) | 2001-2019 | 25.19 | 16.58 | −2.3 (−2.9 to −1.7) | <.001 |
| 75-79 | 8002 (3.5) | 2001-2019 | 21.00 | 15.70 | −1.5 (−2.0 to −1.1) | <.001 |
| 80-84 | 5669 (2.5) | 2001-2019 | 21.98 | 17.56 | −1.5 (−2.1 to −0.8) | <.001 |
| ≥85 | 4883 (2.2) | 2001-2019 | 17.28 | 14.95 | −2.3 (−3.2 to −1.5) | <.001 |
Abbreviations: APC, annual percentage change; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results.
a
The calendar period of each segment was defined based on the identification of calendar years when a statistically significant change in the APC occurred (ie, joinpoint).
b
Rates were calculated as number of cases per 100 000 person-years and age adjusted to the 2000 US population.
c
Year 1 represents the earliest year of the segment.
d
Year 2 represents the latest year of the segment.