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. 2022 Oct 25;87(22):15333–15349. doi: 10.1021/acs.joc.2c01914

Scheme 13. Synthesis of Compound 42.

Scheme 13

Reagents and conditions: (a) p-NO2C6H4CO2H, PPh3, DIAD, PhMe, rt, 40 min, 63%; (b) K2CO3, 2.5:1 EtOH/iPrOH, rt, 48 h, 76%.