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. Author manuscript; available in PMC: 2022 Nov 22.
Published in final edited form as: J Alzheimers Dis. 2019;72(4):1077–1087. doi: 10.3233/JAD-190643

FIGURE 4. APOE ε4/ε4 is associated with higher AMB prevalence only in cases with comorbid LB and CAA pathology in HAD.

FIGURE 4

Each column represents percent of cases with present AMB according to its APOE4 genotype-HAD group. AMB prevalence differences were assessed with an unadjusted logistic regression model using No ε4 & ε4 as an indicator. Number of cases within group reflected within each bar. a) The presence of two copies of ε4 within APOE is significantly associated with AMB prevalence in HAD cases with comorbid LB and CAA (top, left). The presence of two copies of APOE ε4 does is not significantly associated with higher AMB prevalence in HAD cases with b) present LB but absent CAA (top, right), c) absent LB but present CAA (bottom, left) and d) absent LB and CAA pathology (bottom, right). ** refers to p=0.001 significance.