TABLE 3.
Regression analysis of the relationship between APOE4 genotype and presence of AMB in LIAD and High AD load
| Predictors | Odds Ratio (95% CI) |
P value |
|---|---|---|
| LIAD | 0.120 | |
| No ε4 (indicator) | ||
| ε4 | 1.408 (1.008-1.966) |
0.045 |
| ε4/ε4 | 1.356 (0.583-3.153) |
0.480 |
| HAD | ||
| No ε4 (indicator) | 0.001 | |
| ε4 | 1.377 (1.065-1.781) |
0.015 |
| ε4/ε4 | 2.124 (1.504-2.998) |
0.001 |
| ε4 only (indicator) | ||
| ε4/ε4 | 1.542 (1.111-2.140) |
0.010 |
| No ε4 & ε4 (indicator) | ||
| ε4/ε4 | 1.769 (1.297-2.411) |
0.001 |
Table representing the relationship between APOE4 genotype and AMB prevalence in different AD pathological loads. Predictors referred to the presence of one (ε4) or two (ε4/ε4) copies of the ε4 allele of the APOE gene in cases with Low to Intermediate AD load (LIAD) or High AD load (HAD). Numerical values within each column represent Odds Ratio (OR) with associated 95% Confidence Interval (95% CI) and p value. The relationship between APOE4 genotype and AMB prevalence was assessed in an unadjusted logistic regression model.