Poly(I:C) feeding alleviates the immuno-organ injury and strengthen the anti-infection ability. (A) Images of paraffin section in different tissues (including liver, spleen and intestine) of infected turbot larvae (including FD-H, FD-L and FD-N group) at 7 dpi. The white arrows indicated the histopathological injury, scale bar, 20 μm. (B) Percent survival of turbot larvae fed with poly(I:C) after E. piscicida infection. (C) Bacterial burden in gill and intestine of turbot larvae at 7 dpi of E. piscicida infection. * p<0.05, ** p<0.01 and **** p<0.0001.