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. 2022 Aug 24;3:100067. doi: 10.1016/j.fsirep.2022.100067

Table 2.

Scoring details of histopathology analysis in this study.

Observed Tissue Change Scoring
0 1 (Mild) 2 (Moderate) 3 (Severe)
Inflammatory cell infiltrates Not present Infiltration by ≤ 10 mononuclear cells within a 20x field. Infiltration of 11–50 mononuclear cells within a 20x field. Infiltration of ≥ 51 mononuclear cells within a 20x field.
Cellular necrosis Not present Rare pyknosis and/or karyorrhexis of cells affecting ≤ 5% of the entire tissue. Pyknosis and/or karyorrhexis of cells affecting 6–50% of the entire tissue. Widespread pyknosis and/or karyorrhexis affecting ≥ 51% of the entire tissue.
Bacteria Not present Bacteria are present within ≤ two inflammatory cells within a 40x field. Bacteria are present within 3–5 inflammatory cells and/or in a single extracellular aggregates within a 40x field. Bacteria are present within more 5 inflammatory cells and within multiple extracellular aggregates within a 40x field.