Table 2.
Scoring details of histopathology analysis in this study.
Observed Tissue Change | Scoring | |||
---|---|---|---|---|
0 | 1 (Mild) | 2 (Moderate) | 3 (Severe) | |
Inflammatory cell infiltrates | Not present | Infiltration by ≤ 10 mononuclear cells within a 20x field. | Infiltration of 11–50 mononuclear cells within a 20x field. | Infiltration of ≥ 51 mononuclear cells within a 20x field. |
Cellular necrosis | Not present | Rare pyknosis and/or karyorrhexis of cells affecting ≤ 5% of the entire tissue. | Pyknosis and/or karyorrhexis of cells affecting 6–50% of the entire tissue. | Widespread pyknosis and/or karyorrhexis affecting ≥ 51% of the entire tissue. |
Bacteria | Not present | Bacteria are present within ≤ two inflammatory cells within a 40x field. | Bacteria are present within 3–5 inflammatory cells and/or in a single extracellular aggregates within a 40x field. | Bacteria are present within more 5 inflammatory cells and within multiple extracellular aggregates within a 40x field. |