Table 2.
Baseline | 2-week follow-up | 6-week follow-up | Baseline vs 2 weeks | 2 weeks vs 6 weeks | Baseline vs 6 weeks | |||||||
Variable | N | M | SD | N | M | SD | N | M | SD | Wilcoxon signed-rank | Wilcoxon signed-rank | Wilcoxon signed-rank |
PANSS positive | 45 | 11.93 | 4.77 | 36 | 9.17 | 5.36 | 38 | 7.26 | 5.13 | Z=2.76, p=0.006* | Z=2.67, p=0.008* | Z=4.50, p<0.001* |
PANSS negative | 45 | 10.36 | 6.87 | 36 | 10.31 | 7.15 | 38 | 9.58 | 7.78 | Z=0.78, p=0.435 | Z=0.62, p=0.535 | Z=1.17, p=0.242 |
PANSS general | 45 | 19.40 | 8.57 | 36 | 16.64 | 10.60 | 38 | 15.74 | 10.11 | Z=3.21, p=0.001* | Z=2.48, p=0.013* | Z=0.64, p=0.524 |
PANSS total | 45 | 41.69 | 16.11 | 36 | 36.11 | 20.03 | 38 | 32.58 | 20.04 | Z=3.10, p=0.002* | Z=1.46, p=0.144 | Z=3.35, p<0.001* |
BACS verbal memory | 41 | 37.83 | 14.02 | 32 | 41.16 | 13.50 | 36 | 44.56 | 15.02 | Z=−3.14, p=0.002* | Z=−3.15, p=0.002* | Z=−3.88, p<0.001* |
BACS digit sequencing | 38 | 18.03 | 4.06 | 32 | 17.84 | 4.33 | 34 | 17.85 | 4.69 | Z=−0.78, p=0.433 | Z=−0.40, p=0.688 | Z=0.40, p=0.687 |
BACS verbal fluency | 42 | 28.60 | 7.85 | 31 | 31.87 | 9.47 | 35 | 30.20 | 8.38 | Z=−1.96, p=0.050* | Z=0.83, p=0.405 | Z=−1.62, p=0.105 |
BACS token motor | 39 | 65.36 | 10.83 | 32 | 65.56 | 17.81 | 34 | 61.38 | 20.94 | Z=−1.30, p=0.193 | Z=−0.55, p=0.583 | Z=−0.24, p=0.812 |
BACS symbol coding | 39 | 40.15 | 13.13 | 32 | 45.69 | 12.56 | 32 | 47.25 | 11.96 | Z=−2.25, p=0.025* | Z=−1.07, p=0.284 | Z=−3.29, p=0.001* |
BACS ToL | 37 | 14.84 | 4.48 | 29 | 17.38 | 3.29 | 32 | 16.28 | 4.13 | Z=−3.24, p=0.001* | Z=1.45, p=0.148 | Z=−2.42, p=0.016* |
BACS t-score | 33 | 26.67 | 11.98 | 28 | 34.14 | 11.68 | 30 | 30.87 | 14.95 | Z=−3.79, p<0.001* | Z=−0.29, p=0.769 | Z=−3.66, p<0.001* |
BACS z-score | 33 | −2.34 | 1.19 | 28 | −1.59 | 1.17 | 30 | −1.91 | 1.50 | Z=−3.85, p<0.001* | Z=−0.23, p=0.820 | Z=−3.67, p<0.001* |
*Significant at p=0.05 level.
BACS, Brief Assessment of Cognition in Schizophrenia; PANSS, Positive and Negative Symptom Scale; ToL, Tower of London.