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. 2022 Nov 15;11(11):787–802. doi: 10.1302/2046-3758.1111.BJR-2022-0101.R1

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© 2022 Author(s) et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/

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Fig. 7 — Scanning electron microscopy images of Staphylococcus aureus ATCC 25923 biofilm destruction. For all tested CaS/HA-antibiotic groups, biofilm destruction and antibacterial effects were evident on day 7 and day 14. At day 28, number of planktonic bacteria were increased and biofilm were visible. Green arrow indicates biofilm while violet arrow indicates destructed biofilm. Red arrow indicates dead bacteria. Yellow arrow indicates membrane disruption and extravasation of cytoplasmic components of bacteria. Scale bar = 1 μm. CaS/HA, calcium sulphate/hydroxyapatite; GEN, gentamicin; RIF, rifampicin; VAN, vancomycin.