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Kinetic-pharmacodynamic model characterization of mRNAs encoding 3 HIV antibodies. Extrapolated serum levels of bnAbs after 1 mg/kg mRNA dosing up to 90 days following infusion. bnAb, broadly neutralizing antibody; Fc, crystallizable fragment; HIV, human immunodeficiency virus; IgG, immunoglobulin G; scFv, single-chain variable fragment.
