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. Author manuscript; available in PMC: 2022 Nov 22.
Published in final edited form as: Mitochondrion. 2020 Oct 7;55:145–153. doi: 10.1016/j.mito.2020.09.007

Fig. 3.

Fig. 3.

ND4 copy number and ND4 deletion level in plasma and blood cells. The copy number of ND4 in plasma (A) and blood cells (B) in normal patients, patients with thyroid cancer, or patients with thyroid nodules was detected by quantitative fluorescence PCR, and no significant difference was found among the three groups. ND4/ND1 ratio in plasma (C) and in blood cells (D) suggests that there was a greater proportion of intact mtDNA (lesser degree of ND4 deletion) in plasma from thyroid cancer patients compared to both normal patients (P < 0.1) and thyroid nodule patients (P < 0.5). The number below the scatter in the figure is the mean value of each experimental group.