FIG. 2.

Protection against cysticercosis in immunized mice. The individual parasite loads were counted in mice immunized with corresponding antigen 7 weeks after challenge with T. crassiceps cysticerci. The number of completely protected mice of the total number of mice tested in each group is shown above each bar. (A) On days 0, 14, and 28, groups of mice were immunized by i.d. inoculation and boosted two times i.p. with PIgphage (2 × 10¹⁰ phage), nonrelated phage NF (2 × 10¹⁰ phage), and buffer solution (TBS) or free peptide (PT1) (50 μg) in a 200-μl volume. Fourteen days after the last inoculation, the mice were challenged with T. crassiceps cysticerci. (B) Mice were immunized by a single i.d. inoculation with PIgphage (2 × 10¹⁰ phage) and NF (2 × 10¹⁰ phage). Fourteen days later, the mice were challenged with T. crassiceps cysticerci. ∗, contrast with the negative controls (immunized with buffer and nonrelated phage) is statistically significant (P < 0.05).