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Microstructural characterization of platelet-fibrin aggregates. (A) Clots prepared from platelets that were either untreated or treated with blebbistatin, eptifibatide, or T101. Scale bars, 10 μm; Platelets are labeled with AF488-CD42b (green) and fibrinogen with AF594-fibrinogen (red). (B) Average size of platelet aggregates. (C) PCC for the colocalization of platelets and fibrin. Mean ± standard deviation, ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
