Figure 4.

Passive fiber adsorption model. (A) Fibrin fibers (red) are connected to fibrin-bound platelets (yellow), and both fibers are modeled as springs with different stiffnesses. In this passive model, platelets do not exercise any active contractile stress. (B) Description of model elements and boundary conditions. (C) Representative deformation of a five-fiber model with a 5-μm aggregate radius and relative modulus of 10, pulled to 25% uniaxial strain. (D) Strain energy density as a function of relative modulus at various applied strains up to 50%.