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. 2022 Nov 22;12(52):33540–33551. doi: 10.1039/d2ra04725j

Effect of some related drugs on the fluorometric determination of 3 μg mL−1 KPN, 1.5 μg mL−1 PAR and 5 μg mL−1 CLX.

Drug Reason for interference Drug tolerance limit (μg mL−1)
Phenylephrine hydrochloride - It is used to relieve nasal discomfort caused by colds, allergies, and hay fever 173 for KPN 234 for PAR
-Commonly co-administered with PAR or KPN
Tizanidine - Muscle relaxant 112 for KPN 164 for PAR
- Commonly co-administered with PAR or KPN
Venlafaxine - An antidepressant medication 89 for KPN 120 for PAR 125 for CLX
- Could be administered with any of the studied drugs
Diacerein - Used to treat joint diseases such as osteoarthritis 32 for KPN 40 for PAR 48 for CLX
- Could be administered with any of the studied drugs
Diclofenac sodium Analgesic which is commonly prescribed with CLX 50 for CLX
Mefenamic acid Non-steroidal anti-inflammatory drug which is commonly prescribed with CLX 7 for CLX
Aceclofenac Non-steroidal anti-inflammatory drug which is commonly prescribed with CLX 140 for CLX
Ibuprofen Analgesic which is commonly prescribed with CLX 240 for CLX