Figure 2.
Schematic showing potential targets for decreasing liver injury (boxed text) that are not disease specific and may find application in people with HIV.54 Solid arrows indicate impact on disease pathogenesis; dotted arrows denote gut microbiome metabolite leakage into portal circulation. BCAA, branched-chain amino acid; CYP, cytochrome P450; FGF, fibroblast growth factor; FMT, fecal microbiota transplantation; FXR, farnesoid X receptor; LPS, lipopolysaccharide; SCFA, short-chain fatty acid; TLR, toll-like receptor.