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. 2022 Nov 8;13:1011522. doi: 10.3389/fphar.2022.1011522

TABLE 4.

Signs, symptoms, and values of polymerase chain reaction tests at the end of the study among the studied groups.

STD (N = 30) n (%) NS (N = 30) n (%) VD (N = 30) n (%) NS + VD (N = 30) n (%) p-value
Cough (Day +7) 0.02 2
 Absent 8 (26.7) 11 (36.7) 10 (33.3) 15 (50.0)
 Dry 11 (36.7) 18 (60.0) 16 (53.3) 11 (36.7)
 Productive 11 (36.7) 1 (3.3) 4 (13.3) 4 (13.3)
Diarrhea 8 (26.7) 2* (6.7) 1* (3.3) 1* (3.3) 0.01 2
Fatigue (Day +4) 25 (83.3) 12* (40.0) 20* (66.7) 9* (30.0) <0.01 1 **
Headache 14 (46.7) 9 (30.0) 14 (46.7) 6 (20.0) 0.08 1
Rash 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) -
Conjunctivitis 0 (0.0) 1 (3.3) 0 (0.0) 0 (0.0) 1.00 2
Rhinorrhea 4 (13.3) 6 (20.0) 9 (30.0) 3 (10.0) 0.24 2
Anosmia 14 (46.7) 10 (33.3) 13 (43.3) 11 (36.7) 0.71 1
SOB 8 (26.7) 5 (16.7) 6 (20.0) 4 (13.3) 0.60 2
Pharyngitis 9 (30.0) 2* (6.7) 3* (10.0) 2* (6.7) 0.02 1
Ageusia 15 (50.0) 12 (40.0) 15 (50.0) 12 (40.0) 0.75 1
Vomiting 1 (3.3) 0 (0.0) 0 (0.0) 0 (0.0) 1.00 2
PCR positive (day 7) 26 (86.7) 15 (50.0) 25 (83.3) 14 (46.7) <0.01 2 **
PCR positive (day 14) 19* (63.3) 12* (40.0) 14* (46.7) 4* (13.3) <0.01 1 **
1

Pearson’s chi-squared test.

2

Fisher’s exact test.

*Significant difference.

Abbreviations: NS, Nigella sativa; PCR, polymerase chain reaction; SOB, shortness of breath; SO2, oxygen saturation; SOB, shortness of breath; STD, standard therapy; TLC, total leukocyte count; VD, vitamin D3.

Bold value means Significant difference.