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. 2022 Nov 22;11:e79639. doi: 10.7554/eLife.79639

Table 1. Baseline characteristics of the overall study population by type of variant of concern.

Characteristic DeltaN=141 OmicronN=170 p value
Sex (male) – n (%) 69 (48.94) 101 (59.41) 0.068
Age – median (IQR) (range) 65.7 (15.4) (50–92) 64.5 (14.8) (50–90) 0.585
Smoking status – n (%)
Smoker 8 (5.67) 24 (14.12) 0.015
Former smoker 32 (22.70) 28 (16.47) 0.194
Non-smoker 101 (71.63) 118 (69.41) 0.709
BMI – n (%)
≤29 101 (71.63) 132 (77.65) 0.239
≥30 40 (28.37) 38 (22.35) 0.239
SARS-CoV-2 serological status – n (%)
Antibody-positive 70 (49.65) 134 (78.82) <0.001
Antibody-negative 68 (48.23) 35 (20.59) <0.001
Other 3 (2.13) 1 (0.59)
Anti-SARS-CoV-2 vaccination status – n (%)
3 doses or 2 doses ≤120 days 23 (16.31) 66 (38.82) <0.001
1 or 2 doses ≥120 days or not vaccinated 113 (80.14) 99 (58.24) <0.001
Other 5 (3.55) 5 (2.94)
Comorbidities – n (%)
Diabetes 3 (2.13) 6 (3.53) 0.519
Cardiovascular disease 56 (39.72) 61 (35.88) 0.557
Chronic kidney disease 7 (4.96) 9 (5.29) 1.000
Chronic liver disease 3 (2.13) 12 (7.06) 0.061
Chronic pulmonary disease 16 (11.35) 33 (19.41) 0.061
Immunocompromising conditions 17 (12.06) 35 (20.59) 0.048
Symptoms at enrolment – n (%)
Cough 96 (68.09) 118 (69.41) 0.807
Nasal congestion 69 (48.94) 69 (40.59) 0.169
Sore throat 32 (22.70) 69 (40.59) 0.001
Feeling hot or feverish 103 (73.05) 99 (58.24) 0.008
Myalgia 46 (32.62) 54 (31.76) 0.903
Fatigue 47 (33.33) 75 (44.12) 0.062
Headache 59 (41.84) 60 (35.29) 0.244
Anosmia/ageusia 39 (27.66) 4 (2.35) <0.001
Nausea/vomiting 28 (19.86) 11 (6.47) <0.001
Diarrhoea 15 (10.64) 12 (7.06) 0.314
Serum C-reactive protein level – n 136 161
Mean (SD), mg/L 20.58 (29.00) 14.29 (21.72) 0.022