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. 2022 Oct 1;12(4):e2022140. doi: 10.5826/dpc.1204a140

Table 2.

Selected clinical features of vitiligo patients and serum Cu and Zn levels

Group Cu (μg/ dl)
Median
Cu (μg/dl)
Mean ± SD
Pa Zn (μg/ dl)
Median
Zn (μg/dl)
Mean ± SD
Pa [Cu]/[Zn] pa

Early Onset < 50 (59.83%) 95.07 107.12 ± 61.17 0.035 72.56 83.06 ± 49.89 0.001 1.96 ± 1.44 0.164
Late Onset >50 (40.17%) 138.37 122.53 ±56.30 100.23 112.81± 67.19 1.72 ± 2.13

Early-Onset (<50 y)
Male (23.9%) 98.41 110.78± 62.80 0.189 76.92 89.70±45.13 0.008 1.73± 1.61 0.00
Female (35.8%) 90.04 116.54±54.15 68.96 78.63±52.90 1.77± 2.00

Late-Onset (>50 Y)
Male (17.1%) 131.69 119.65±57.57 0.017 88.58 113.54±78.26 0.629 1.49 ± 1.11 0.005
Female (24.7%) 128.67 124.52±56.34 100.23 112.27± 59.25 2.54±2.79

Clinical type
Generalized (82.9%) 101.96 111.63±54.18 0.04 73.01 93.11±59.33 0.006 1.88±2.02 0.078
Localized (17.09%) 104.72 120.74 ±71.64 110.50 98.69±58.63 1.40±1.24

Skin phototype
Skin type I and II (0%)
Skin type III (69.93%) 103.41 112.67±59.66 0.113 84.68 99.24± 59.91 0.015 1.48± 1.16 0.00
Skin type IV (29.97%) 103.61 117.04± 59.95 67.32 86. 16±60.62 2.45±2.75

History of other auto immune disease
Yes (6.84%) 136.36 143.99±62.61 0.001 74.48 98.29±68.92 0.008 2.08±1.33 0.00
No (93.16%) 98.15 111.34±58.89 77.08 94.71± 58.59 1.79± 1.96

Smoking status
Smokers (16.23%) 99.86 106.93 ± 57.08 0.023 74.03 99.67 ± 59.49 0.05 1.71± 1.63 0.273
Non-smokers (83.76%) 103.51 115.45 ± 60.20 76.25 94.34± 59.50 1.83±1.95

Cu = copper; SD = standard deviation; Y = years; Zn = zinc.

Pa, case –case comparison.