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. 2022 Nov 15;2022:1330928. doi: 10.1155/2022/1330928

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Copyright © 2022 Mengxia Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of the ERα inhibitor MPP on cerebral infarction volume, cerebral water content, and neurological function in HIBD newborn mice. (a) TTC staining photos of brain tissue sections, n = 6 mice in each group. (b) Quantitative analysis of cerebral infarct volume shown by TTC staining. (c) Quantitative analysis of brain water content in HIBD pups, n = 6 mice in each group. (d) Quantitative analyses of body weight, (e) righting reflex, (f) negative geotaxis, and (g) grip tests on days 1, 3, 5, and 7 after HIBD in neonatal mice, n = 8 mice in each group. ^∗∗∗P < 0.001 and ^∗∗∗∗P < 0.0001 compared with the HI + ICA + Vehicle group, NS = no significant difference. Data are presented as the mean ± SDs.