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. 2022 Jul;12(Suppl 1):S5–S14. doi: 10.5005/jp-journals-10018-1361

Table 3.

Univariate analysis of variables and effect on outcomes at 1 year in ≥20% steatosis

Recipient Graft survival Mortality
HR (95% CI) p HR (95% CI) p
Age 1.00 (0.99–1.01) 0.69 1.01 (1.00–1.02) 0.05
BMI 1.01 (0.99–1.02) 0.27 1.01 (0.99–1.03) 0.77
MELD 1.02 (1.01–1.03) <0.001 1.03 (1.02–1.04) <0.001
Etiology of LT
  Noncholestatic liver disease Ref ref
  Acute liver failure 1.62 (0.99–2.33) 0.06 1.68 (1.06–2.67) 0.03
  Cholestatic liver disease 0.87 (0.63–1.22) 0.42 0.87 (0.56–1.21) 0.32
  Malignant neoplasm 0.86 (0.67–1.10) 0.24 0.85 (0.64–1.13) 0.26
  Other 1.36 (0.99–1.87) 0.06 1.2 (0.822–1.76) 0.34
Vent support at LT 3.01 (2.19–4.13) <0.001 3.04 (2.12–4.36) <0.001
Donor
  Age 1.01 (1.0–1.02) 0.006 1.01 (1.00 –1.01) 0.1
  BMI 1.0 (0.99–1.01) 0.85 1.00 (0.99–1.01) 0.95
  Gender—female 0.95 (0.8–1.11) 0.5 0.92 (0.76–1.1) 0.35
Race
  Caucasian Ref ref
  Hispanic 1.17 (0.94–1.47) 0.17 1.11 (0.85–1.43) 0.44
  AA 0.97 (0.75–1.25) 0.8 0.89 (0.66–1.2) 0.44
  Asian 1.1 (0.67–1.82) 0.7 1.14 (0.66–2.0) 0.64
  Other 1.31 (0.75–2.27) 0.34 1.27 (0.68–2.39) 0.45
HCV Ab+ 0.69 (0.45–1.06) 0.09 0.73 (0.46–1.18) 0.2
HBV NAT+ 0.0 (0.0–0.0) 0.96 0.0 (0.0–0.0) 0.97
Heavy alcohol use 1.02 (0.85–1.23) 0.85 1.02 (0.83–1.26) 0.85
Hypertension 1.24 (1.05–1.46) 0.001 1.09 (0.91–1.31) 0.35
Diabetes 1.13 (0.93–1.38) 0.21 1.03 (0.82–1.3) 0.78
DCD 1.09 (0.63–1.89) 0.75 0.98 (0.51–1.89) 0.94
CIT 1.04 (1.02–1.07) 0.0003 1.03 (1.01–1.06) 0.02
COD
  Anoxia ref ref
  CVA 1.83 (1.49–2.25) <0.001 1.88 (1.48–2.39) <0.001
  Head trauma 1.38 (1.08–1.77) 0.011 1.54 (1.16–2.04) 0.003
  CNS tumor 1.55 (0.57–4.18) 0.39 1.56 (0.5–4.94) 0.45
  Unknown 1.36 (0.69–2.67) 0.38 1.83 (0.92–3.63) 0.084
DRI 1.18 (1.03–1.35) 0.018 1.16 (0.99–1.35) 0.07

AA, African American; Ab, antibody; BMI, body mass index; CIT, cold ischemic time; CVA, cerebrovascular accident; DCD, deceased after cardiac death; DRI, donor risk index; HBV, hepatitis B virus; HCV, hepatitis C virus; LT, liver transplantation; MELD, model for end-stage liver disease; NAT, nucleic acid amplification