Table 3.
Recipient | Graft survival | Mortality | ||
---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Age | 1.00 (0.99–1.01) | 0.69 | 1.01 (1.00–1.02) | 0.05 |
BMI | 1.01 (0.99–1.02) | 0.27 | 1.01 (0.99–1.03) | 0.77 |
MELD | 1.02 (1.01–1.03) | <0.001 | 1.03 (1.02–1.04) | <0.001 |
Etiology of LT | ||||
Noncholestatic liver disease | Ref | ref | ||
Acute liver failure | 1.62 (0.99–2.33) | 0.06 | 1.68 (1.06–2.67) | 0.03 |
Cholestatic liver disease | 0.87 (0.63–1.22) | 0.42 | 0.87 (0.56–1.21) | 0.32 |
Malignant neoplasm | 0.86 (0.67–1.10) | 0.24 | 0.85 (0.64–1.13) | 0.26 |
Other | 1.36 (0.99–1.87) | 0.06 | 1.2 (0.822–1.76) | 0.34 |
Vent support at LT | 3.01 (2.19–4.13) | <0.001 | 3.04 (2.12–4.36) | <0.001 |
Donor | ||||
Age | 1.01 (1.0–1.02) | 0.006 | 1.01 (1.00 –1.01) | 0.1 |
BMI | 1.0 (0.99–1.01) | 0.85 | 1.00 (0.99–1.01) | 0.95 |
Gender—female | 0.95 (0.8–1.11) | 0.5 | 0.92 (0.76–1.1) | 0.35 |
Race | ||||
Caucasian | Ref | ref | ||
Hispanic | 1.17 (0.94–1.47) | 0.17 | 1.11 (0.85–1.43) | 0.44 |
AA | 0.97 (0.75–1.25) | 0.8 | 0.89 (0.66–1.2) | 0.44 |
Asian | 1.1 (0.67–1.82) | 0.7 | 1.14 (0.66–2.0) | 0.64 |
Other | 1.31 (0.75–2.27) | 0.34 | 1.27 (0.68–2.39) | 0.45 |
HCV Ab+ | 0.69 (0.45–1.06) | 0.09 | 0.73 (0.46–1.18) | 0.2 |
HBV NAT+ | 0.0 (0.0–0.0) | 0.96 | 0.0 (0.0–0.0) | 0.97 |
Heavy alcohol use | 1.02 (0.85–1.23) | 0.85 | 1.02 (0.83–1.26) | 0.85 |
Hypertension | 1.24 (1.05–1.46) | 0.001 | 1.09 (0.91–1.31) | 0.35 |
Diabetes | 1.13 (0.93–1.38) | 0.21 | 1.03 (0.82–1.3) | 0.78 |
DCD | 1.09 (0.63–1.89) | 0.75 | 0.98 (0.51–1.89) | 0.94 |
CIT | 1.04 (1.02–1.07) | 0.0003 | 1.03 (1.01–1.06) | 0.02 |
COD | ||||
Anoxia | ref | ref | ||
CVA | 1.83 (1.49–2.25) | <0.001 | 1.88 (1.48–2.39) | <0.001 |
Head trauma | 1.38 (1.08–1.77) | 0.011 | 1.54 (1.16–2.04) | 0.003 |
CNS tumor | 1.55 (0.57–4.18) | 0.39 | 1.56 (0.5–4.94) | 0.45 |
Unknown | 1.36 (0.69–2.67) | 0.38 | 1.83 (0.92–3.63) | 0.084 |
DRI | 1.18 (1.03–1.35) | 0.018 | 1.16 (0.99–1.35) | 0.07 |
AA, African American; Ab, antibody; BMI, body mass index; CIT, cold ischemic time; CVA, cerebrovascular accident; DCD, deceased after cardiac death; DRI, donor risk index; HBV, hepatitis B virus; HCV, hepatitis C virus; LT, liver transplantation; MELD, model for end-stage liver disease; NAT, nucleic acid amplification