Table 2.

Clinical features of Cushing syndrome and prevalence

Signs/symptoms of Cushing syndrome	Prevalence (%)
(Abdominal) obesity/weight gain	75-95
Rounded face (moon face)	81-90
Supraclavicular/dorsocervical fat pad (buffalo hump)	50
Hirsutism/alopecia	75
Facial plethora	70-90
Violaceous striae	44-50
Acne	20-35
Easy bruising	35-65
Menstrual irregularity	70-80
Decreased libido	24-80
Neuropsychiatric (emotional lability/depression, psychosis/mania, cognitive dysfunction)	70-85
Muscle weakness/atrophy	60-82
Osteopenia/fractures	40-70

Features with highest discriminatory value are depicted in bold. Table adapted from Sharma et al (5).