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. 2022 Jun 30;24(6):986–994. doi: 10.1007/s11307-022-01749-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Cervical nodal metastasis with high FAPI uptake and low FDG uptake maximum intensity projections (A, B) and axial fusion images of a 73-year-old male with nasopharyngeal cancer prior to radiation therapy. The patient was upstaged with newly emerged nodal metastasis on both sides of the neck, noticed only in the FAP scans (C, D; white arrows). [.⁶⁸ Ga]-FAPI PET/CT also revealed one cervical lymph node metastasis in close proximity to the cervical spinal cord (at C4 level) that would have been missed in the FDG-scans (E, F; yellow arrows).