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. Author manuscript; available in PMC: 2022 Nov 23.
Published in final edited form as: Stem Cell Res. 2022 Jul 11;63:102855. doi: 10.1016/j.scr.2022.102855
Unique stem cell lines identifier 1. SCVIi049-A
2. SCVIi050-A
Alternative name(s) of stem cell lines 1. SCVIi049-A / SCVI104
2. SCVIi050-A / SCVI2486
Institution Stanford Cardiovascular Institute, Stanford, CA, US
Contact information of distributor Joseph C. Wu, joewu@stanford.edu
Type of cell lines iPSC
Origin Human
Additional origin info required for human ESC or iPSC Age: 44 (SCVIi049-A) and 30 (SCVIi050-A)
Sex: male
Ethnicity if known: Not Hispanic or Latino
Cell Source Fibroblast (SCVIi049-A), PBMC (SCVIi050-A)
Clonality Clonal
Method of reprogramming Nonintegrating Sendai virus expression of human OCT4, SOX2, KLF4, and c-MYC
Genetic Modification Yes
Type of Genetic Modification Spontaneous mutation
Evidence of the reprogramming transgene loss (including genomic copy if applicable) RT-qPCR
Associated disease Dilated cardiomyopathy (DCM)
Gene/locus PLN (6q22.31)
SCVIi049-A: heterozygous PLN (c.25C > T)
SCVIi050-A: heterozygous PLN (c.40_42delAGA)
Date archived/stock date SCVIi049-A: 09/10/2019
SCVIi050-A: 12/03/2021
Cell line repository/bank https://hpscreg.eu/cell-line/SCVIi049-A
https://hpscreg.eu/cell-line/SCVIi050-A
Ethical approval The generation of the lines was approved by the Administrative Panel of Human Subjects Research (IRB) under IRB #29904 “Derivation of Human Induced Pluripotent Stem Cells”