Table 3.
The evaluation results of DeepPROTACs, SVM, and RF models on test set
| Model | Fingerprints | Average accuracy | AUROC |
|---|---|---|---|
| DeepPROTACs | - | 77.46% | 0.8531 |
| SVM | MACCS | 71.48% | 0.7385 |
| Morgan | 76.76% | 0.8196 | |
| RF | MACCS | 68.31% | 0.7973 |
| Morgan | 69.37% | 0.8117 |
The evaluation results of DeepPROTACs, SVM, and RF models on test set
| Model | Fingerprints | Average accuracy | AUROC |
|---|---|---|---|
| DeepPROTACs | - | 77.46% | 0.8531 |
| SVM | MACCS | 71.48% | 0.7385 |
| Morgan | 76.76% | 0.8196 | |
| RF | MACCS | 68.31% | 0.7973 |
| Morgan | 69.37% | 0.8117 |