FIGURE 8.

In vivo efficacy of SB-T-121605. (A) Changes of tumor volume (%) during experiment in comparison to situation before the first application. Efficacy was compared between control group, experimental group treated with 10 mg/kg PTX alone, and groups treated with combinations of a/9 mg/kg PTX with 1 mg/kg SB-T-121605, b/7 mg/kg PTX with 3 mg/kg SB-T-121605, and c/5 mg/kg PTX with 5 mg/kg SB-T-121605. (B) Changes of mouse weight (g) during the application in all examined experimental groups. *p-values by two-tailed Student´s t-test (*p ≤ 0.05).