Table 2.

Median change in each outcome variable by timepoint specified (units per year).

	6-Month	12-Month	18-Month	24-Month
Median MDS-UPDRS total score change (Q1, Q2)	0 (−6, 6)	0.5 (−6, 7.75)	3 (−5, 10)	5 (−3, 13)
Median LEDD change (Q1, Q2)	0 (0, 93.75)	0 (0, 199.5)	90 (0, 230.25)	119.5 (0, 350)
Median PDQ39 change (Q1, Q2)		0 (−2.5, 5)		2.5 (0, 10)
Median MoCA change (Q1, Q2)		0 (−1, 1)		−1 (−2, 1)
Median S&E change (Q1, Q2)		0 (−0.1, 0)		0 (−0.1, 0)
Median GCO change (Q1, Q2)		0.04 (−0.18, 0.28)		0.23 (−0.05, 0.53)

Q₁: 25th percentile; Q₂: 75th Percentile.