Table 3.
Average in-sample (training set) and out-of-sample (testing set) accuracy (standard deviation) of ridge regression to predict change in six metrics from baseline to 6, 12, 18, and 24 months.
| 6-Month | 12-Month | 18-Month | 24-Month | |||||
|---|---|---|---|---|---|---|---|---|
| In-sample | Out-of-sample | In-sample | Out-of-sample | In-sample | Out-of-sample | In-sample | Out-of-sample | |
| iSway 1 | ||||||||
| MDS-UPDRS Total score | 76.23% (0.64%) |
72.46% (6.53%) |
56.14% (1.27%) |
48.29% (7.37%) |
62.86% (0.78%) |
55.49% (7.3%) |
66.02% (0.77%) |
58.55% (8.4%) |
| LEDD | 53.25% (1.16%) |
45.53% (8.29%) |
62.11% (0.86%) |
53.43% (7.39%) |
61.98% (0.75%) |
56.65% (7.39%) |
66.53% (0.77%) |
58.75% (8.61%) |
| PDQ39 | 59.16% (0.94%) |
54.98% (8.55%) |
55.69% (1.24%) |
46.77% (7.44%) |
||||
| MoCA | 54.02% (0.92%) |
47.22% (8.27%) |
54.06% (0.79%) |
47.43% (6.84%) |
||||
| Schwab | 58.43% (1.36%) |
51.52% (9.19%) |
64.8% (0.83%) |
60.05% (7.74%) |
||||
| GCO | 53.67% (0.81%) |
49.61% (9.37%) |
61.39% (0.72%) |
54.48% (7.5%) |
||||
| iSway 2 | ||||||||
| MDS-UPDRS Total score | 75.47% (0.65%) |
71.17% (6.98%) |
58.06% (0.82%) |
52.35% (7.12%) |
63.88% (0.73%) |
57.47% (7.17%) |
65.23% (0.79%) |
59.4% (8.3%) |
| LEDD | 52.27% (1.05%) |
49.31% (8.75%) |
60.91% (0.83%) |
53.6% (7.52%) |
60.49% (0.8%) |
56.66% (7.64%) |
64.97% (0.87%) |
57.96% (8.64%) |
| PDQ39 | 60.83% (0.85%) |
55.12% (8.74%) |
55.1% (1.01%) |
51.77% (7.82%) |
||||
| MoCA | 53.77% (1.16%) |
42.76% (8.22%) |
55.74% (0.81%) |
48.12% (6.95%) |
||||
| Schwab | 61.39% (0.8%) |
55.7% (8.87%) |
63.93% (0.85%) |
59.79% (7.93%) |
||||
| GCO | 53.04% (0.94%) |
50.32% (9.41%) |
59.92% (0.7%) |
55.24% (7.45%) |
||||
| iTUG | ||||||||
| MDS-UPDRS Total score | 75.84% (0.65%) |
67.64% (8.22%) |
60.45% (1.16%) |
51.55% (8.19%) |
66.48% (0.78%) |
56.08% (8.08%) |
71.62% (0.83%) |
58.21% (8.87%) |
| LEDD | 57.75% (1.68%) |
41.45% (8.31%) |
58.57% (0.97%) |
51.7% (8.29%) |
62.95% (0.86%) |
55.17% (8.35%) |
63.04% (0.87%) |
55.58% (8.82%) |
| PDQ39 | 64.06% (0.8%) |
57.27% (9.19%) |
58.56% (0.75%) |
53.09% (7.87%) |
||||
| MoCA | 52.39% (2.42%) |
43.36% (9.04%) |
60.13% (0.87%) |
52.97% (8.28%) |
||||
| Schwab | 59.25% (0.67%) |
54.93% (9.17%) |
69.17% (0.86%) |
55.66% (7.82%) |
||||
| GCO | 50.59% (2.54%) |
45.28% (9.8%) |
70.43% (0.69%) |
57.37% (7.9%) |
||||
| iSway 1 + iTUG | ||||||||
| MDS-UPDRS Total score | 76.04% (0.65%) |
66.97% (7.91%) |
60.86% (1.23%) |
49.93% (8.21%) |
68.89% (0.78%) |
55.51% (8.14%) |
73.95% (0.72%) |
57.12% (9.23%) |
| LEDD | 58.75% (1.45%) |
42.43% (8.27%) |
57.84% (1.21%) |
49.89% (8.33%) |
62.22% (0.86%) |
54.41% (8.16%) |
62.2% (0.84%) |
54.61% (8.83%) |
| PDQ39 | 63.13% (0.82%) |
56.93% (8.99%) |
59.9% (1.05%) |
52.14% (7.97%) |
||||
| MoCA | 53.45% (2.43%) |
41.84% (8.79%) |
58.5% (0.93%) |
50.47% (8.42%) |
||||
| Schwab | 60.23% (0.74%) |
53.83% (9.36%) |
71.43% (0.72%) |
56.4% (8.03%) |
||||
| GCO | 52.12% (2.02%) |
47.23% (9.74%) |
71.92% (0.67%) |
58.1% (7.71%) |
||||
| iSway 2 + iTUG | ||||||||
| MDS-UPDRS Total score | 74.05% (0.62%) |
66.74% (7.92%) |
60.44% (1.3%) |
51.55% (8.07%) |
68.29% (0.73%) |
56.28% (7.87%) |
70.25% (0.71%) |
57.19% (8.99%) |
| LEDD | 57.94% (1.2%) |
45% (8.47%) |
58.57% (1.02%) |
51.21% (8.17%) |
62.7% (0.83%) |
54.2% (8.19%) |
61.88% (0.83%) |
54.38% (8.6%) |
| PDQ39 | 63.55% (0.75%) |
57.17% (8.87%) |
60.72% (0.98%) |
53.69% (8.24%) |
||||
| MoCA | 52.7% (2.38%) |
41.34% (8.87%) |
58.85% (0.92%) |
51.22% (8.33%) |
||||
| Schwab | 61.15% (0.83%) |
55.62% (9.4%) |
57.12% (1.96%) |
50.73% (8.66%) |
||||
| GCO | 51.96% (1.92%) |
47.49% (9.79%) |
69.01% (0.77%) |
56.22% (8.31%) |
||||