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. 2022 Nov 21;12:20060. doi: 10.1038/s41598-022-24657-w

Table 2.

Characteristics at enrolment of subjects who had AFL, dyspnoea or both at follow-up (N = 5086).

AFL at follow-up Dyspnoea at follow-up AFL with dyspnoea at follow-up Normal at follow-up
N 449 1,021 100 3716
Age, years 63 (± 8)* 61 (± 9)* 64 (± 8)* 58 (± 9)
Female, N (%) 202 (45)* 702 (69) 50 (50)* 2564 (69)
Height, cm 162 (± 8)* 158 (± 8) 161 (± 8)* 159 (± 8)
Weight, kg 59 (± 10)* 58 (± 10)* 59 (± 11)* 57 (± 10)
BMI, kg/m2 22.4 (± 2.8) 23 (± 3.3)* 22.8 (± 3.3) 22.3 (± 2.9)
Smoking status, N (%) 219 (49)* 307 (30) 48 (48)* 1052 (28)
Current 98 (22)* 131 (13) * 27 (27)* 328 (9)
Former 121 (27)* 176 (17) 21 (21) 724 (19)
Pulmonary function test
%FEV1, % 96 (± 14)* 103 (± 15)* 94 (± 14)* 106 (± 14)
%FVC, % 99 (± 16)* 99 (± 15)* 98 (± 15)* 102 (± 14)
FEV1/FVC 0.76 (± 0.04)* 0.82 (± 0.05)* 0.76 (± 0.04)* 0.83 (± 0.05)
Comorbidities, N (%)
Hypertension 128 (29)* 303 (30)* 30 (30)* 792 (21)
Diabetes 31 (7) 72 (7) 6 (6) 229 (6)
Cardiovascular disease 23 (5) 77 (8)* 11 (11)* 133 (4)

All values are expressed as the mean (± SD) except categorical variables, which are expressed as N (%). SD standard division, AFL airflow limitation, BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity. *P < 0.05, compared with normal subjects without AFL or dyspnoea at follow-up.